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What is childhood Hodgkin Lymphoma Cancer Disease?

What is childhood Hodgkin Lymphoma Cancer Disease?

Childhood Hodgkin Lymphoma Cancer

Childhood Hodgkin Lymphoma DiseaseChildhood Hodgkin lymphoma is a form of childhood cancer in which malignant cancer cells begin to grow within the lymph system. The lymph system plays a critical role in the body’s immune system, which, when functioning properly, keeps us well by fighting bacteria, viruses, and other foreign disease-causing invaders. The lymph system is a network of tissues found throughout the body and connected by tube-like lymph vessels. Critical parts of the lymph system include:

  • Lymph nodes: small, bean-like sacs found throughout the body, responsible for clearing the body of germs and cell waste. Lymph nodes can be found in the neck, armpit, abdomen, pelvis, and groin.
  • Lymphocytes: a type of white blood cell responsible for fighting infection and disease. Lymphocytes can be either B cells or T cells; most Hodgkin lymphomas start in B cell lymphocytes.
  • Lymph: a colorless fluid that carries lymphocytes through lymph vessels around the body.
  • Spleen: an organ located near the stomach, responsible for making lymphocytes, filtering blood, and storing and destroying blood cells.
  • Thymus: an organ located in the chest, responsible for storing lymphocytes as they grow and multiply.
  • Tonsils: Small masses of lymph tissue found at the back of the throat, responsible for making new lymphocytes.
  • Bone marrow: located within the center of large bones, the bone marrow creates white blood cells, red blood cells, and platelets.

Hodgkin Lymphoma almost always begins in B lymphocytes. Classical Hodgkin lymphoma is characterized by the presence of Reed-Sternberg cells and can be further divided into four sub-types, dependent on the appearance of the cancer cells under a microscope:

  • Lymphocyte-rich classical Hodgkin lymphoma.
  • Nodular sclerosis Hodgkin lymphoma.
  • Mixed cellularity Hodgkin lymphoma.
  • Lymphocyte-depleted Hodgkin lymphoma.

A much more rare form of Hodgkin lymphpoma is known as Nodular lymphocyte-predominant Hodgkin lymphoma and is characterized by lymphocyte-predominant cells instead of Reed-Sternberg cells. This type of cancer may, in some cases, evolve into diffuse large B-cell lymphoma.

Incidence of Hodgkin Lymphoma in Children

Unlike most forms of childhood cancer, Hodgkin lymphoma can develop similarly in both children and adults. In children, Hodgkin lymphoma makes up about 6% of all childhood cancers. In the United States, it occurs most often in adolescents aged 15-19 years and least often in children under the age of 4, although in developing countries, children under 10 have a much higher incidence of Hodgkin lymphoma while the incidence for adolescences is similar to that in the United States. Within adolescents in the United States, more girls than boys develop Hodgkin lymphoma, while for children under 5, the disease is much more likely to develop in boys.

Five-year survival rates for Hodgkin lymphoma have increased greatly over the past 30 years, with many adolescents especially responding well to chemotherapy and low-dose radiation therapy similar to adult protocols for the same disease. The five-year survival rate for Hodgkin lymphoma is now close to 95%, although as with all forms of childhood cancer, the prognosis for each specific child/adolescent depends greatly on the unique nature of the cancer and the “stage” the cancer has reached at the time of diagnosis. Moreover, Hodgkin lymphoma survivors are at high risk of long-term health problems stemming from the necessary adult-focused treatment options.

About American Childhood Cancer Organization

American Childhood Cancer Organization (ACCO) is a non-profit charity dedicated to helping kids with cancer and their families navigate the difficult journey from cancer diagnosis through survivorship. Internationally, ACCO is the sole U.S. member of Childhood Cancer International (CCI), the largest patient-support organization for childhood cancer in the world. Here in the United States, ACCO promotes the critical importance of ensuring continued funding into new and better treatment protocols for childhood cancer.  And most importantly, ACCO is focused on the children: developing and providing educational tools for children fighting cancer and their families, empowering them in their understanding of childhood cancer and the medical decisions they must make during this difficult journey. All of ACCO’s resources are available free of charge for families coping with childhood cancer.

More about Childhood Hodgkin Lymphoma Cancers:

Learn More About the Different Types of Childhood Cancers:

For additional information about childhood cancer or on the ACCO, or to order resources for you or your child, please visit our website at , call 855.858.2226 or visit:

Gold Ribbon Hero Emily N

“Reason this person is a Gold Ribbon Hero: Emily is a brave 3yr old girl who is fighting Medduloblastoma.” – Christy N



Emily N

Gold Ribbon Hero Alyssa K

“Reason this person is a Gold Ribbon Hero: Alyssa was diagnosed with Hepatoblastoma (liver cancer)August 2016. Through the whole process she has shown extreme strength while enduring very difficult times.” – Shaun K


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Gold Ribbon Hero Tobias G

“Reason this person is a Gold Ribbon Hero: Toby relapsed ALL in January of this year and since then they have hit him extremely hard with chemo after chemo. He has pulled through with amazing strength, he pushes past the pain he feels with smiles and laughter. He never lets cancer get him down or discourage him, and in moments of weakness he pulls through with his faith in God having a big plan for him. He amazes me and his strength shows mine up on a daily bases.” – Jennifer G


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Gold Ribbon Hero Eli W

“Reason this person is a Gold Ribbon Hero: September of 2014, my son, Eli, was diagnosed with alveolar soft part sarcoma.  He has endured 2 tumors, 3 surgeries, 33 days of radiation, and countless scans.  This coming April, it will be 2 years since he finished his radiation so he will have an MRI on his brain and leg plus a CT.  To date all his scans have been clear.  Through this whole adventure,  Eli has made it so easy for everyone else with his great attitude!  He continues to do well in school, play his sports, and be with his friends.  Love him so much!” – Elizabeth W



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Hauling Away Childhood Cancer


Thursday, March 23rd-Saturday March 25th

Hours: 1-6p Thursday, 10-6p Friday, 9-4p Saturday

Kentucky Expo Center: 937 Phillips Lane Louisville, KY 40209

Tickets can be purchased online or at the door for $10.

Join Randy M. Manning LLC at the Mid-Atlantic Truck Show for the unveiling of their new childhood cancer awareness truck!

Over 1,000 exhibitors will be in attendance, representing leading companies from the US and abroad- ALL THINGS TRUCKS!

This event is family-friendly, fun, and is a great way to raise awareness by “Hauling Away Childhood Cancer”!

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To register for this event, and for more details, click HERE.

If you are planning to attend, make sure you look for their booth in the WEST WING of the Expo Center!


Come support kids with cancer during one of the Nation’s largest truck shows. The $10 registration fee gets you into the event all three days, with a complimentary concert on Friday night! If you are coming from out-of-town and need travel information, please visit this link or url:

There will be a “truck seat” raffle and all proceeds benefit the American Childhood Cancer Organization (ACCO). There will also be lots of fun ACCO childhood cancer awareness items to purchase as well.

Approximately, 75,000 people attend this event over the three day period. There will be vendors, displays, demonstrations, entertainment, food and drink, and of course, a good amount of large trucks for the entire family to view. Below are some links to more details about the event:

Tickets are only $10 and are available online through this link (the button above) or at the door. It’s best to purchase tickets in advance as you are able to avoid the lines. Once you register, print out your confirmation page and bring it with you to the event. Each person attending will have to register separately and the printout will need to be exchanged for a badge.

Thank you in advance for your participation and ongoing support for ACCO. We hope to see you there!